Circumscribed palmar hypokeratosis (CPH) is a benign entity first described by Pérez et al1 in 2002. It consists of a thinning of the stratum corneum and is more common in women than in men.1,2 The cause is unknown but has been proposed to be a localized disorder of a clone of keratinocytes.2,3
Vilas Boas da Silva PT, Rodríguez-Lomba E, Avilés-Izquierdo JA, Ciudad-Blanco C, Suárez-Fernández R. Dermoscopic Features of Circumscribed Palmar Hypokeratosis. JAMA Dermatol. 2017;153(6):609–611. doi:10.1001/jamadermatol.2017.0015
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