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Comment & Response
June 2017

Detection of Occult Invasion in Melanoma in Situ—Reply

Author Affiliations
  • 1Department of Dermatology, University of Michigan, Ann Arbor
  • 2Department of Pathology, University of Michigan, Ann Arbor
  • 3Division of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor
  • 4Department of Otolaryngology, University of Michigan, Ann Arbor
JAMA Dermatol. 2017;153(6):611-612. doi:10.1001/jamadermatol.2017.0197

In Reply We thank Rodic and Glusac for their insightful comments on our article. First, we would like to emphasize that in all cases reclassified as microinvasive melanoma, the dermal cells possessed cytopathologic features of melanoma cells (large size, ample cytoplasm, and/or visible nucleoli) appreciable on melan-A stain alone or in conjunction with hematoxylin-eosin (H&E) stain.1

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