In 1910, Frederic Edward Mohs, MD, was born in Burlington, Wisconsin. Although initially he trained to become a radio engineer, Dr Mohs transitioned to medicine in college.1 While he attended medical school at the University of Wisconsin, he worked with Dr Michael Guyer, a cancer researcher, and cultivated an interest in preparing frozen tissue for histological study. Here, he made the vital discovery that zinc chloride paste could “fix” skin tissue for microscopic examination, setting the foundation for the Mohs micrographic surgery (MMS) technique.2
Sood A, Ayyaswami V, Prabhu AV, Benedek TG. Frederic Edward Mohs, MD—The Pioneer of Chemosurgery. JAMA Dermatol. 2017;153(6):522. doi:10.1001/jamadermatol.2017.0723
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