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Jalenques I, Rondepierre F, Massoubre C, et al. Treatment of Psychiatric Disorders and Skin-Restricted Lupus Remission: A Longitudinal Study. JAMA Dermatol. 2017;153(12):1331–1332. doi:https://doi.org/10.1001/jamadermatol.2017.3590
Skin-restricted lupus erythematosus (SRL) comprises discoid lupus erythematosus (DLE), lupus tumidus (LT), and subacute cutaneous lupus erythematosus (SCLE). We and others reported a high prevalence of psychiatric disorders (PD), often undertreated, in patients with SRL.1,2 However, the impact of PDs and psychotropic medications on skin disease outcome has not been described. Thus, we decided to investigate this relationship in a patient cohort over 2.5 years.
After providing written informed consent, 75 patients with DLE, LT, or SCLE, prospectively recruited, were assessed by a dermatologist and a psychiatrist every 6 months over 2.5 years. The dermatologist recorded whether the SRL was in remission as defined by the complete absence of inflammatory lesions. More details can be found in previous article.1 This study received approval from the local ethical review board.
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