Incidence of primary and secondary syphilis in the United States nearly quadrupled from 2000, when 5979 cases were reported, to 2015, when 23 872 cases were reported.1 This syphilis epidemic has disproportionately affected men who have sex with men (MSM), who accounted for nearly 60% of cases in 2015.1 Public health efforts to prevent and control syphilis among MSM focus on ensuring early diagnosis and prompt treatment of infected patients and their sex partners.2 We describe a patient with an evolving clinical and serologic presentation of penile sores, ultimately leading to diagnosis of and treatment for primary syphilis.
Gao Y, Katz KA. Clinical and Serologic Evolution of Multiple Penile Chancres in a Man Who Has Sex With Men. JAMA Dermatol. 2018;154(1):108–109. doi:10.1001/jamadermatol.2017.3958
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