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January 2018

Topical Tacalcitol for Family Occurrence of Follicular Keratosis of the Chin

Author Affiliations
  • 1Division of Pediatric Dermatology, University Children’s Hospital Zurich, Zurich, Switzerland
  • 2Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
  • 3Private dermatology practice, Zurich, Switzerland
JAMA Dermatol. 2018;154(1):111-112. doi:10.1001/jamadermatol.2017.4418

Follicular keratosis of the chin (FKC) is a rare and poorly understood disorder of childhood with a characteristic presentation of multiple, closely set, hyperkeratotic follicular papules on the chin or jaw. We report 2 new cases of FKC in 2 brothers and propose topical tacalcitol as an effective treatment option.

A 7-year-old boy and his 5-year-old brother were seen for papular lesions on the chin that had occurred at age 4 years in both cases. On examination, both children had multiple whitish, follicular, hyperkeratotic, pinpoint papules on their chins, more pronounced in the older boy (Figure 1). The lesions were asymptomatic, and the boys were otherwise in good general health. A habit of rubbing or picking or any other physical trauma was denied. Because of the distinct clinical presentation, a diagnosis of FKC was made. Dermoscopy findings were also consistent with this disorder, showing well-demarcated yellow spindle bodies (Figure 2).1