Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare life-threatening cutaneous drug reactions. The pathogenesis is imperfectly understood and includes genetic factors.1 Pregnant women with SJS or TEN are a unique subset, and both conditions can simultaneously affect the mother and fetus.2-4 There are no data on the risk of SJS or TEN in a newborn of a mother who develops the condition during pregnancy if soon after delivery the newborn is given the same drug that triggered the mother’s reaction. We report the case of a pregnant woman with SJS whose newborn was successfully treated with the drugs responsible for his mother’s SJS.
Velter C, Hotz C, Ingen-Housz-Oro S, Wolkenstein P, Fardet L. Stevens-Johnson Syndrome During Pregnancy: Case Report of a Newborn Treated With the Culprit Drug. JAMA Dermatol. 2018;154(2):224–225. doi:10.1001/jamadermatol.2017.4607
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