In this issue of JAMA Dermatology, 2 large, well-constructed studies remind dermatologists that even though pyoderma gangrenosum (PG) is a quintessential disease in medical dermatology, we still need data to better define the disease and reduce the risk of cognitive biases. We know the results of these biases well; even at referral centers and in clinical trials, alternative diagnoses can prevail 7% to 20% of the time.1,2 In these articles, one of the largest retrospective PG databases and a new tool for PG diagnosis validation are presented.3,4
Kaffenberger BH, Trinidad J. Diagnosis uPGrade—Advances in Pyoderma Gangrenosum. JAMA Dermatol. Published online February 14, 2018. doi:10.1001/jamadermatol.2017.5979
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