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Comment & Response
May 2018

Utility of Baseline Transaminase Monitoring During Systemic Terbinafine Therapy for Pediatric Onychomycosis

Author Affiliations
  • 1Department of Dermatology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts
JAMA Dermatol. 2018;154(5):626-627. doi:10.1001/jamadermatol.2018.0094

To the Editor We applaud the important research findings by Patel et al1 regarding pediatric onychomycosis. In this study, the authors appropriately conclude that routine laboratory monitoring of children during treatment with terbinafine may be unnecessary, considering (1) the low incidence of clinically significant adverse effects; (2) the costs of laboratory tests; (3) workup of spurious laboratory abnormalities; and (4) patient discomfort.

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