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May 2018

Hair Loss Associated With Cucurbit Poisoning

Author Affiliations
  • 1Centre Sabouraud, Saint Louis Hospital, Paris, France
JAMA Dermatol. 2018;154(5):617-618. doi:10.1001/jamadermatol.2017.6128

Hair loss induced by plant ingestion, a classic cause of toxic anagen effluvium, is rare. The most commonly involved plants are colchicum, tubers of Gloriosa superba, Lecythis ollaria, and Leucaena leucocephala (containing mimosine).1 The implicated mechanism of toxic effects from these plants on the hair follicle seems mainly due to their antimitotic action.