[Skip to Content]
[Skip to Content Landing]
Review
August 2018

Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis FoundationA Systematic Review

Author Affiliations
  • 1Keck School of Medicine, University of Southern California, Los Angeles
  • 2National Psoriasis Foundation, Portland, Oregon
  • 3Psoriasis Treatment Center of Central New Jersey, East Windsor
  • 4Department of Dermatology, University of California San Francisco
  • 5Department of Pediatrics, University of California San Francisco
  • 6Department of Dermatology, Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
  • 7New York Medical College at Metropolitan Hospital, New York
  • 8Hudson Dermatology, Somers, New York
  • 9Department of Dermatology, George Washington University School of Medicine, Washington, DC
  • 10Department of Dermatology, University of Michigan, Ann Arbor
  • 11Icahn School of Medicine at Mount Sinai, New York, New York
  • 12Northwestern University Feinberg School of Medicine, Chicago, Illinois
  • 13Hospital for Special Surgery, Weill Medical College of Cornell University, New York-Presbyterian Hospital, New York
  • 14National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland
  • 15Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
  • 16Blackrock Clinic, Dublin, Ireland
  • 17Arthritis and Rheumatism Associates, PC, Rockville, Maryland
  • 18Georgetown University School of Medicine, Washington, DC
  • 19Department of Dermatology, Eastern Virginia Medical School, Norfolk
  • 20Department of Dermatology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
JAMA Dermatol. 2018;154(8):934-950. doi:10.1001/jamadermatol.2018.1412
Key Points

Question  What dietary interventions help adult patients with psoriasis and/or psoriatic arthritis reduce their disease severity?

Findings  In this systematic review of 55 studies and 4534 patients with psoriasis, we identify the strongest evidence for dietary weight reduction with a hypocaloric diet in overweight and obese patients with psoriasis. The utility of gluten-free diet and supplementation with vitamin D varies by subpopulations of adults with psoriatic diseases, and evidence is low for the utility of specific foods, nutrients, and dietary patterns in reducing psoriatic disease activity.

Meaning  Adults with psoriasis and/or psoriatic arthritis can supplement their medical therapies with dietary interventions to reduce disease severity.

Abstract

Importance  Psoriasis is a chronic, inflammatory skin disease and has significant associated morbidity and effect on quality of life. It is important to determine whether dietary interventions help reduce disease severity in patients with psoriatic diseases.

Objective  To make evidence-based dietary recommendations for adults with psoriasis and/or psoriatic arthritis from the Medical Board of the National Psoriasis Foundation.

Evidence Review  We used literature from prior systematic reviews as well as additional primary literature from the MEDLINE database from January 1, 2014, to August 31, 2017, that evaluated the impact of diet on psoriasis. We included observational and interventional studies of patients with psoriasis or psoriatic arthritis. The quality of included studies was assessed using the Newcastle-Ottawa scale for observational studies and the Cochrane Risk of Bias Tool for interventional studies. We made evidence-based dietary recommendations, which were voted on by the National Psoriasis Foundation Medical Board.

Findings  We identified 55 studies meeting the inclusion criteria for this review. These studies represent 77 557 unique participants of which 4534 have psoriasis. Based on the literature, we strongly recommend dietary weight reduction with a hypocaloric diet in overweight and obese patients with psoriasis. We weakly recommend a gluten-free diet only in patients who test positive for serologic markers of gluten sensitivity. Based on low-quality data, select foods, nutrients, and dietary patterns may affect psoriasis. For patients with psoriatic arthritis, we weakly recommend vitamin D supplementation and dietary weight reduction with a hypocaloric diet in overweight and obese patients. Dietary interventions should always be used in conjunction with standard medical therapies for psoriasis and psoriatic arthritis.

Conclusions and Relevance  Adults with psoriasis and/or psoriatic arthritis can supplement their standard medical therapies with dietary interventions to reduce disease severity. These dietary recommendations from the National Psoriasis Foundation Medical Board will help guide clinicians regarding the utility of dietary interventions in adults with psoriatic diseases.

×