In Reply We thank Marghoob et al for the opportunity to address their concerns regarding our study.1 Number needed to biopsy (NNB) (or excise) is a well-established measure consistent with prior publications,2-4 including studies by Marghoob and colleagues.3,4 While NNB can vary with disease prevalence, patients in both cohorts in our study had similar rates of keratinocyte carcinomas and invasive melanomas. Patients were also similarly distributed by age and sex, and our NNB findings remained consistent when patients with a melanoma history were excluded.
Ferris LK, Anderson AM, Matsumoto M. Performance of Dermatology Physician Assistants—Reply. JAMA Dermatol. 2018;154(10):1229–1230. doi:10.1001/jamadermatol.2018.2696
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