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November 14, 2018

Dupilumab Treatment for Generalized Prurigo Nodularis

Author Affiliations
  • 1Department of Dermatology, University of California, San Francisco, San Francisco
JAMA Dermatol. Published online November 14, 2018. doi:10.1001/jamadermatol.2018.3912

Generalized prurigo nodularis is a severe and widespread morphologic manifestation of chronic pruritus.1 This condition is challenging to treat and results in a high burden of disease.1 We examined the effectiveness of the interleukin (IL) 4 receptor α inhibitor dupilumab as a novel treatment option for generalized prurigo nodularis.