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Comment & Response
January 2019

Use of Combination Systemic-Intratumoral HPV Vaccine to Treat Cutaneous Basaloid Squamous Cell Carcinomas

Author Affiliations
  • 1Department of Dermatology, Bichat Claude Bernard Hospital, AP-HP, Paris, France
  • 2Department of Pathology, Bichat Claude Bernard Hospital, AP-HP, Paris, France
  • 3INSERM UMR-1137, IAME, University of Paris Diderot, Sorbonne Paris Cité, Laboratoire de Virologie, Hôpital Bichat
JAMA Dermatol. 2019;155(1):123-124. doi:10.1001/jamadermatol.2018.3789

To the Editor We read with great interest the article by Nichols et al1 regarding the use of combined systemic and intratumoral human papillomavirus (HPV) vaccine to treat a woman in her 90s with multiple cutaneous squamous cell carcinomas. This article drew our attention because of the difficulties encountered in the management of such lesions in elderly patients. In the reported case, it seems clear that neither surgery nor chemotherapy would have been suitable for the patient.

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