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Research Letter
April 10, 2019

Influence of “Not Relevant” Responses on the Dermatology Life Quality Index (DLQI) for Patients With Psoriasis in the United States

Author Affiliations
  • 1Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia
JAMA Dermatol. 2019;155(6):743-745. doi:10.1001/jamadermatol.2018.5655

The Dermatology Life Quality Index (DLQI) is a popular health-related quality-of-life measure in dermatology. However, there are concerns that scoring “not relevant” responses as equivalent to “not at all” may bias the DLQI toward underestimating severity of disease, and recent studies of patients with psoriasis in Europe found that those who responded “not relevant” had more severe disease than those who responded “not at all.”1,2 Given cross-cultural differences in response patterns, the purpose of this study was to evaluate whether a similar association exists for the English-language DLQI administered to patients with psoriasis in the United States.3

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