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Research Letter
May 8, 2019

Psoriasis and Risk of Mental Disorders in Denmark

Author Affiliations
  • 1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
  • 2Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark
  • 3Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
  • 4Department of Affective Disorders, Department of Psychiatry, Aarhus University Hospital, Aarhus, Denmark
  • 5Aarhus Institute of Advanced Studies, Aarhus University, Denmark
  • 6Department of Radiology, Aarhus University Hospital, Aarhus, Denmark
JAMA Dermatol. 2019;155(6):745-747. doi:10.1001/jamadermatol.2019.0039

Psoriasis has been reported to be associated with an elevated risk of various mental disorders, including depression, anxiety, and suicidality.1 However, to our knowledge, no studies have determined the long-term risk of a broader spectrum of adult-onset mental disorders in a large cohort of individuals with psoriasis. Given the high prevalence of psoriasis—between 2% and 4% in adults2—investigation of the association of this condition with mental health has important public health implications. Therefore, we aimed to elucidate the association between psoriasis and the entire spectrum of adult-onset psychiatric morbidity. The study was approved by the Danish Data Protection Agency, whose role is to protect the privacy of individuals whose data are recorded in Danish registries. No informed consent was required for this study.