Avoiding General Anesthesia in Treating Port-Wine Stains in Infants to Avoid Neurotoxic Events: Risk-Benefit Ratio Still Undefined

To the Editor We read with interest the study by Jeon et al¹ on the use of pulsed-dye laser to treat port-wine stain in infants without the need for general anesthesia. The editorial by Mathes and Frieden² nicely summarizes the risks of untreated pain on subsequent behavior, even for relatively minor procedures such as vaccination. The shared decision-making vision presented by Mathes and Frieden is an essential part of daily practice, grounded in a careful consideration of risks, benefits, and alternatives based on the available evidence.