In Reply We agree with the conclusion of Haydar et al that carefully collected and concrete safety data are of paramount importance in determining the value of laser treatment of port-wine stains in infants. In fact, in our study,1 we evaluated the safety of this procedure and demonstrated evidence in over 1700 treatments in 197 infants without a single case of scarring or pigmentary change. This safety profile is in large part dependent on the use of the proper technology that results in selective vascular injury with epidermal protection using dynamic cooling, as well as a nonoverlapping technique of carefully delivering the laser pulses within a therapeutic range of laser parameters.
Geronemus RG, Jeon H, Bernstein LJ. Avoiding General Anesthesia in Treating Port-Wine Stains in Infants to Avoid Neurotoxic Events—Reply. JAMA Dermatol. Published online July 03, 2019. doi:10.1001/jamadermatol.2019.1133
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