A number of myositis-specific autoantibodies have been identified in patients with dermatomyositis (DM), including anti–aminoacyl-transfer RNA synthetase (ARS), antimelanoma differentiation-associated protein 5 (MDA5), and antitranscriptional intermediary factor 1 (TIF1)γ antibodies, each of which is respectively associated with characteristic cutaneous manifestations.1,2 We analyzed the histologic findings of finger lesions based on these 3 myositis-specific autoantibodies.
Okiyama N, Yamaguchi Y, Kodera M, et al. Distinct Histopathologic Patterns of Finger Eruptions in Dermatomyositis Based on Myositis-Specific Autoantibody Profiles. JAMA Dermatol. Published online July 10, 2019155(9):1080–1082. doi:10.1001/jamadermatol.2019.1668
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