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July 24, 2019

Coinfection With Talaromyces marneffei and Other Pathogens Associated With Acquired Immunodeficiency

Author Affiliations
  • 1Department of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China
  • 2Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China
JAMA Dermatol. 2019;155(10):1195-1197. doi:10.1001/jamadermatol.2019.1532

We report the case of a patient with different skin lesions following concomitant or sequential Talaromyces marneffei infection and other opportunistic infections associated with neutralizing antiinterferon (IFN)-γ autoantibodies. This type of infection should be considered in the differential diagnosis of patients who are HIV negative and infected with T marneffei.

A woman in her 40s presented with a 9-month history of intermittent fever, fatigue, cough, thoracodynia, and multiple skin nodules and abscesses. She resided in a rural area village in Guangxi, in southern China. Her medical history and family history were unremarkable.

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