[Skip to Content]
[Skip to Content Landing]
Views 411
Citations 0
Research Letter
November 6, 2019

Prevalence of Pemphigoid as a Potentially Unrecognized Cause of Pruritus in Nursing Home Residents

Author Affiliations
  • 1Center for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
  • 2Department of General Practice and Elderly Care Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
JAMA Dermatol. Published online November 6, 2019. doi:https://doi.org/10.1001/jamadermatol.2019.3308

Bullous pemphigoid may commonly present as pruritus in elderly patients.1 Approximately 1 in 5 patients with pemphigoid has nonbullous skin manifestations that resemble other pruritic skin diseases, termed nonbullous pemphigoid.1,2 According to recently established minimal diagnostic criteria, the diagnosis of bullous and nonbullous pemphigoid can be based on either a skin biopsy or a serum sample.2 The prevalence of bullous pemphigoid strongly increases with age, and the disease is associated with neurodegenerative diseases such as dementia and Parkinson disease.3,4 Our aim was to assess the prevalence of pemphigoid in a high-risk population of nursing home residents, with nonbullous pemphigoid as a potentially unrecognized cause of pruritus.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words