Bullous pemphigoid may commonly present as pruritus in elderly patients.1 Approximately 1 in 5 patients with pemphigoid has nonbullous skin manifestations that resemble other pruritic skin diseases, termed nonbullous pemphigoid.1,2 According to recently established minimal diagnostic criteria, the diagnosis of bullous and nonbullous pemphigoid can be based on either a skin biopsy or a serum sample.2 The prevalence of bullous pemphigoid strongly increases with age, and the disease is associated with neurodegenerative diseases such as dementia and Parkinson disease.3,4 Our aim was to assess the prevalence of pemphigoid in a high-risk population of nursing home residents, with nonbullous pemphigoid as a potentially unrecognized cause of pruritus.
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Meijer JM, Lamberts A, Luijendijk HJ, et al. Prevalence of Pemphigoid as a Potentially Unrecognized Cause of Pruritus in Nursing Home Residents. JAMA Dermatol. Published online November 06, 2019. doi:https://doi.org/10.1001/jamadermatol.2019.3308
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