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JAMA Dermatology Clinicopathological Challenge
November 20, 2019

A Solitary Nodular Vulvar Lesion

Author Affiliations
  • 1Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
  • 2Department of Pathology, Hospital Universitario Fundación Alcorcón, Madrid, Spain
  • 3Department of Dermatology, Hospital Universitario de Móstoles, Madrid, Spain
JAMA Dermatol. 2020;156(1):96-97. doi:10.1001/jamadermatol.2019.3446

A girl in her teens presented with a unilateral itchy nodule on her right labium majus of 4 months’ duration. The patient was born and lived in a rural village in Malawi. Her medical and family history were unremarkable. She did not report fever or malaise. Physical examination revealed a polypoid, rubbery tumor measuring 1.5 cm located on her right labium majus, which obliterated the right labium minus (Figure, A). She did not present with enlarged lymph nodes, and results of the physical examination were otherwise unremarkable. An incisional lesional biopsy was taken (Figure, B and C).

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