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November 20, 2019

Extracellular Crystal Deposition in Cutaneous Plasmacytosis

Author Affiliations
  • 1Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Republic of Korea
JAMA Dermatol. 2020;156(2):217-218. doi:10.1001/jamadermatol.2019.3401

Cutaneous plasmacytosis is a rare skin disorder that is most often seen in Asian individuals. It is characterized by multiple reddish-brown to dark-brown plaques, mainly on the trunk. Histologically, the plaques contain a marked dermal infiltrate of mature plasma cells without cellular atypia.1 Extracellular crystal deposition is a rare but documented finding in plasma cell myeloma, which is characterized by the expansion of a single immunoglobulin-secreting plasma cell clone.2 In this article, we report a case of extracellular crystal deposition found in the skin of a patient with cutaneous plasmacytosis.

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