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JAMA Dermatology Clinicopathological Challenge
January 2, 2020

Recurrent Blistering in an Infant

Author Affiliations
  • 1Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  • 2Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
JAMA Dermatol. 2020;156(2):212-213. doi:10.1001/jamadermatol.2019.4038

An infant boy, born to a nonconsanguineously wed couple, presented to the dermatology outpatient clinic with recurrent skin blisters since age 2 months. The lesions initially started over the trunk and subsequently progressed to involve the face, hands, and feet. The episodes of skin blisters were accompanied by pruritus and redness all over the body. There was no history of oral erosions or difficulty in feeding. Bowel and bladder movements were normal. The child had an older sibling who had no skin ailments, and none of the other family members were affected.

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