Erosive lichen planus of the vulva (ELPV) is a subtype of lichen planus characterized by desquamative, erosive dermatitis involving the vulva and vagina. Management of ELPV is challenging; almost 25% of patients have ELPV that is resistant to first-line therapy with topical corticosteroids.1,2 There are very few studies of ELPV, which makes management of recalcitrant ELPV difficult. Specifically, little evidence is available on methotrexate (MTX) for the treatment of recalcitrant ELPV. The aim of this study was to retrospectively review medical records to evaluate the efficacy of treatment with MTX in women with ELPV at a vulvar clinic.
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Cline A, Cuellar-Barboza A, Jorizzo JL, Pichardo RO. Methotrexate for the Treatment of Recalcitrant Erosive Lichen Planus of the Vulva. JAMA Dermatol. Published online January 02, 2020. doi:10.1001/jamadermatol.2019.4062
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