[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 35.170.75.58. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 526
Citations 0
JAMA Dermatology Clinicopathological Challenge
February 12, 2020

A Treatment-Refractory, Perianal Tumor Arising in an Otherwise Healthy Older Adult Woman

Author Affiliations
  • 1Department of Dermatology, Oregon Health and Science University, Portland
JAMA Dermatol. Published online February 12, 2020. doi:10.1001/jamadermatol.2019.4823

A woman in her 80s presented with an 8-month history of a growing, painful tumor on her right buttock. The patient felt well otherwise and denied experiencing fevers, chills, sweats, weight loss, or malaise. Her medical history was notable for chronic kidney disease and genital herpes simplex virus (HSV). She reported no history of genital warts, HIV, or inflammatory bowel disease. A biopsy was performed, and results were consistent with a noninfectious, granulomatous ulcer. Based on the clinical appearance and prior pathologic findings, the patient received treatment of oral antibiotics, intralesional steroids, topical steroids, and immunomodulators, without improvement. Findings from colorectal surgical evaluation of the internal anal mucosa were negative for malignant neoplasm.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×