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Images in Dermatology
May 6, 2020

Necrobiotic Xanthogranuloma

Author Affiliations
  • 1Department of Dermatology, Hospital Santa Casa de Curitiba, Curitiba, Paraná, Brazil
  • 2Department of Hematology, Hospital Santa Casa de Curitiba, Curitiba, Paraná, Brazil
JAMA Dermatol. Published online May 6, 2020. doi:10.1001/jamadermatol.2020.0897

A woman in her 40s came to our hospital for evaluation of asymptomatic yellow plaques on her eyelids (Figure), which had been present for 8 years. Within the past 5 years, she had developed similar plaques on her trunk and limbs with rapid evolution in size and subsequent ulceration. During this period, the patient also developed dysphagia, dysphonia, diffuse lymphadenopathy, and splenomegaly.

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