[Skip to Content]
[Skip to Content Landing]
Views 1,470
Citations 0
June 10, 2020

Diet and Acne—Challenges of Translating Nutritional Epidemiologic Research Into Clinical Practice

Author Affiliations
  • 1Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia
JAMA Dermatol. Published online June 10, 2020. doi:10.1001/jamadermatol.2020.1601

There is growing evidence that diet may influence the incidence and severity of acne vulgaris, one of the most common skin conditions in the US.1 Much of the previous literature on the role of diet in acne has focused on the association of milk consumption and high glycemic-load diet with acne. For instance, milk consumption is thought to increase insulin and insulinlike-growth factor 1 levels, which can induce lipogenesis and proliferation of both keratinocytes and sebocytes.2,3 In addition, insulinlike-growth factor 1 can stimulate androgen synthesis and decrease production of sex hormone–binding globulin. Bovine insulinlike-growth factor 1 and androgens present in milk may also promote the development of acne.2,3

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words