[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 831
Citations 0
Research Letter
July 15, 2020

Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

Author Affiliations
  • 1Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
  • 2Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
JAMA Dermatol. Published online July 15, 2020. doi:10.1001/jamadermatol.2020.2195

LIPH pathogenic variants are a major cause of autosomal recessive woolly hair/hypotrichosis (ARWH; OMIM 278150/604379). To our knowledge, there have been no effective treatments for ARWH, although some reports have found topical minoxidil to improve hypotrichosis.1 We report the results of a prospective nonrandomized clinical trial involving 8 Japanese patients with ARWH carrying LIPH pathogenic variants.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words