In Reply We thank Brownstone and Koo for their interest and response to our systematic review1 reporting on models of care for patients with psychocutaneous conditions and acknowledgment of the subpopulation of patients with Morgellons disease. Within our article, we report patients with a diagnosis of delusions of parasitosis (DoP) to represent the largest proportion among all included individuals with various psychodermatologic conditions. Because of the complex, growing, and difficult-to-manage nature of Morgellons disease, increased awareness and special considerations are called for while treating affected patients.