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Research Letter
December 9, 2020

Spectrum of Nail Sequelae in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Author Affiliations
  • 1Department of Dermatology, Singapore General Hospital, Singapore
  • 2Duke-National University of Singapore Graduate Medical School, Singapore
JAMA Dermatol. 2021;157(1):117-119. doi:10.1001/jamadermatol.2020.4664

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) constitute a spectrum of severe cutaneous adverse drug reactions characterized by differing extents of cutaneous detachment. There is growing recognition that survivors experience various sequelae with long-term morbidity. Finger and toenail deformities have been observed in up to 50% of patients1-3; however, the spectrum of these changes has yet to be clearly established. We seek to document the incidence of various nail changes as sequalae to SJS/TEN.

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