[Skip to Navigation]
Views 6,376
Citations 0
JAMA Dermatology Clinicopathological Challenge
February 17, 2021

Multiple, Tender Perianal Ulcers in a Young Woman

Author Affiliations
  • 1Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut
  • 2Department of Pathology, Yale University School of Medicine, New Haven, Connecticut
JAMA Dermatol. 2021;157(4):458-459. doi:10.1001/jamadermatol.2020.5764

A woman in her late 30s was evaluated by the dermatology inpatient consult service for a 4-day history of perianal pain. Her medical history included systemic lupus erythematosus, antiphospholipid antibody syndrome, and external hemorrhoids. Six months before admission, she underwent a deceased donor kidney transplant. One month before presentation, she was hospitalized for acute cellular transplant rejection managed with systemic corticosteroids, belatacept, mycophenolate mofetil, and tacrolimus therapies. Her immunosuppressive regimen at the time of dermatologic evaluation consisted of prednisone, 5 mg daily, and mycophenolate mofetil, 500 mg twice daily.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words