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JAMA Dermatology Clinicopathological Challenge
March 17, 2021

Progressive Papular Eruption of the Distal Upper Extremities in a Patient With Asymptomatic Papules

Author Affiliations
  • 1Department of Dermatology, Mayo Clinic, Jacksonville, Florida
JAMA Dermatol. Published online March 17, 2021. doi:10.1001/jamadermatol.2021.0188

A woman in her 30s presented with a chronic history of slowly expanding asymptomatic papules on the dorsal hands since childhood, with more recent involvement of both forearms. She denied photosensitivity, arthritis, or muscle weakness. Examination revealed multiple discrete reddish-brown, well-defined, smooth 2- to 6-mm dome-shaped papules (Figure, A). There were no nail changes or mucous membrane involvement.

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