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January 2005

Sentinel Lymph Node Biopsy in Recessive Dystrophic Epidermolysis Bullosa and Squamous Cell Carcinoma

Arch Dermatol. 2005;141(1):110-111. doi:10.1001/archderm.141.1.110

Squamous cell carcinoma (SCC) is the most common cause of death in patients with recessive dystrophic epidermolysis bullosa (RDEB).1 In the Hallopeau-Siemens type, the cumulative risk is 76.5% by age 60 years.2 The sentinel lymph node (SLN) biopsy technique enables the early detection of micrometastasis not only in melanoma but also in other skin malignancies such as high-risk SCC or Merkel cell carcinoma.3

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