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Off-Center Fold
January 2005

Subcutaneous Nodules on the Face—Quiz Case

Author Affiliations


Arch Dermatol. 2005;141(1):93-98. doi:10.1001/archderm.141.1.93-g

A 65-year-old woman presented with a 2-year history of diffuse facial swelling and firm subcutaneous nodules involving the glabella, cheeks, submentum, and lips (Figure 1). One month earlier, she had developed indurated, erythematous papules over her knees and right forearm. Fifteen years earlier, she had received liquid silicone injections to her glabella, nasolabial folds, and marionette lines.