Immunocompromised individuals constitute the majority of patients diagnosed as having cryptococcosis1; however, with improving antiretroviral agents for patients with AIDS, organ transplant recipients are at the highest risk of acquiring the infection. A recent review studied the incidence of Cryptococcus neoformans in transplant recipients and found that the mean incidence of infection was 2.8 per 100 transplant recipients, while the overall death rate was 72 (42%) of 172 recipients.2