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July 2005

Erythematous and Hypopigmented Patches on the Face—Diagnosis

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Copyright 2005 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2005

Arch Dermatol. 2005;141(7):897-902. doi:10.1001/archderm.141.7.897-b

Histopathologic examination of the skin biopsy specimen showed mucin accumulation within sebaceous glands and the external root sheaths of hair follicles. Also, the dermis contained a mixed inflammatory infiltrate of lymphocytes, histiocytes, and eosinophils (Figure 2). The hair follicles were also markedly dilated and showed cyst formation (Figure 3). Mucicarmine staining revealed cystic spaces filled with mucin. No epidermotropism, Pautrier microabscesses, or atypical lymphocytes with mitotic figures were observed. Physical examination and laboratory investigations, including blood tests, radiography of the chest, and ultrasonography of the abdomen, revealed no abnormalities.

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