The best results in vitiligo treatment with tacrolimus ointment have been obtained in summer and on UV light–exposed areas, which suggests that UV light enhances the efficacy of tacrolimus ointment.1- 5 We performed a prospective intra-individual left/right comparison pilot study to evaluate the efficacy of 0.1% tacrolimus ointment as true monotherapy with no UV light exposure (artificial or natural).
Nima Ostovari, Thierry Passeron, Jean-Philippe Lacour, Jean-Paul Ortonne. Lack of Efficacy of Tacrolimus in the Treatment of Vitiligo in the Absence of UV-B Exposure. Arch Dermatol. 2006;142(2):252–253. doi:10.1001/archderm.142.2.252