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March 2006

Sex Differences in the Transmission, Prevention, and Disease Manifestations of Sexually Transmitted Diseases

Author Affiliations

Author Affiliations: Center for Clinical Studies (Dr Madkan) and Department of Dermatology, The University of Texas Health Science Center at Houston (Drs Giancola and Tyring), Houston, Tex; and Department of Dermatology, University of Texas Medical Branch, Galveston (Dr Sra).

Arch Dermatol. 2006;142(3):365-370. doi:10.1001/archderm.142.3.365

Background  Dermatological manifestations of sexually transmitted diseases (STDs) range from full body papulosquamous eruptions to genital ulcers and warts. The transmission, prevalence, and disease burden of STDs are not shared equally between the sexes.

Observations  Women are more susceptible than men for the acquisition of the human immunodeficiency virus and other dangerous STDs because of economic, biological, and social factors, and often sustain more damage to their health from the disease.

Conclusion  This review article elucidates the differential effect of STDs on women vs men to better understand what is required to protect women from the morbidity and mortality of STDs.