A 47-year-old man presented with a nodule on his right thigh that had been present since childhood. He stated that the lesion had been stable in size for decades but had been slowly enlarging over the past 3 years. He complained that the lesion was mildly tender and that it continually caught on his clothing. He had a history of hepatitis C but no personal or family history of cancer.
Physical examination revealed a 1.7-cm smooth, well-defined, firm, violaceous nodule on the right thigh (Figure 1). The lesion was excised and sent for histologic analysis (Figure 2 and Figure 3).
Stewart DB, Egbert BM, Rouse RV, Swetter SM. Slow-Growing Nodule on the Thigh—Quiz Case. Arch Dermatol. 2006;142(7):921–926. doi:10.1001/archderm.142.7.921-d