Palmoplantar keratodermas (PPKs) are heterogeneous disorders that are characterized by abnormal keratinization of palmar and plantar skin.1 Type I hereditary punctate PPK (Buschke-Fischer-Brauer keratoderma) is an inherited autosomal dominant variant with variable penetrance.1-5
Erkek E, Erdogan S, Tuncez F, et al. Type I Hereditary Punctate Keratoderma Associated With Widespread Lentigo Simplex and Successfully Treated With Low-Dose Oral Acitretin. Arch Dermatol. 2006;142(8):1065–1086. doi:10.1001/archderm.142.8.1076
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