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Evidence-Based Dermatology: Research Commentary
September 2006

Tacrolimus and Pimecrolimus for Atopic Dermatitis: Where Do They Fit In?

Arch Dermatol. 2006;142(9):1203-1205. doi:10.1001/archderm.142.9.1203

Question: For adults and children with atopic dermatitis, which are more effective and better tolerated in reducing the signs and symptoms of atopic dermatitis: topical pimecrolimus, tacrolimus, corticosteroids, or vehicle?

Design: Systematic review and meta-analysis.

Data Sources: Electronic searches of the Cochrane Library database, MEDLINE, and EMBASE.

Study Selection: Randomized controlled trials of topical pimecrolimus or tacrolimus reporting efficacy outcomes or tolerability.