Histologic sections demonstrated occasional necrotic keratinocytes within the epidermis and vacuolar alteration of the basal layer. A superficial and bandlike infiltrate of lymphocytes and histiocytes and mucin deposition were noted in the dermis. The patient's serum sample was positive for antinuclear, anti-SSA/Ro, and anti-SSB/La antibodies and negative for anti-U1RNP, anti-Smith, anti–Jo-1, and anti–Scl-70 antibodies. Her electrocardiograms revealed no abnormalities. Serologic studies of the mother's serum sample revealed anti-SSA/Ro and anti-SSB/La antibodies as well as an antinuclear antibody titer of 1:320 in a speckled pattern. The mother had no symptoms of autoimmunity.
Multiple Annular Plaques in an Infant—Diagnosis. Arch Dermatol. 2006;142(10):1351–1356. doi:10.1001/archderm.142.10.1351-e
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: