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January 2007

Effect of Tacrolimus on Vitiligo in Absence of UV Radiation Exposure

Author Affiliations

Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007

Arch Dermatol. 2007;143(1):115-126. doi:10.1001/archderm.143.1.119

We read with interest the article by Ostovari et al,1 who elegantly surmised that UV light is essential for tacrolimus to work. In our vitiligo clinic we have been studying the pattern of repigmentation of vitiligo with tacrolimus, the stability of this pigment, and the site variation for the last 2 years. We believe that there is sufficient evidence to show that tacrolimus monotherapy is useful to produce repigmentation.2