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July 2007

Paraneoplastic Relapsing Polychondritis

Arch Dermatol. 2007;143(7):945-955. doi:10.1001/archderm.143.7.949

I read with interest the report by Yanagi et al1 in which the authors not only describe a 60-year-old Japanese woman with newly diagnosed relapsing polychondritis 3 years following the detection and subsequent successful treatment of stage IIA splenic non-Hodgkin lymphoma but also speculate that some cases of relapsing polychondritis may be paraneoplastic. Mucocutaneous paraneoplastic syndromes may be associated with hematologic malignant neoplasms, solid tumors, or both.2 Also, albeit less commonly, individuals with cancer may concurrently or sequentially demonstrate more than 1 mucocutaneous paraneoplastic syndrome.3,4

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