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May 1, 2008

Classic Mediterranean Kaposi’s Sarcoma Regression With Sirolimus Treatment

Arch Dermatol. 2008;144(5):692-693. doi:10.1001/archderm.144.5.692

Replacement of mycophenolate mofetil, cyclosporine, or tacrolimus by sirolimus results in regression of Kaposi's sarcoma (KS) in organ transplant recipients.1-3 In these patients, clearance from KS might result either from reduced immunosuppression or from the direct antiangiogenic effects of sirolimus.

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