Pyoderma gangrenosum is an idiopathic, rapidly evolving, severely debilitating neutrophilic dermatosis, typically characterized by an inflammatory ulcer with a purulent infiltrated border.1 About two-thirds of pyoderma gangrenosum are associated with systemic diseases, mostly inflammatory bowel diseases (either ulcerative colitis or Crohn disease), but also with monoclonal gammapathies and myeloproliferative disorders.