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June 1, 2008

Giant Subcutaneous Tumors on the Thighs—Diagnosis

Author Affiliations


Arch Dermatol. 2008;144(6):795-800. doi:10.1001/archderm.144.6.795-e

Histopathologic analysis demonstrated mature adipocytes, keloidal collagen, and multiple fibroblasts with slender dendritic processes within a myxoid stroma. No lipoblasts were seen. The dendritic cells stained positive for CD34; the adipocytes stained positive for S-100; and the Ki-67 stain showed a low growth fraction. The larger tumor was then completely removed by simple excision. The excised tumor weighed more than 145 kg. The second tumor was scheduled to be excised at a later date, after the first incision site was healed.