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August 18, 2008

Eczematoid Graft-vs-Host Disease—Reply

Arch Dermatol. 2008;144(8):1066-1067. doi:10.1001/archdermatol.2008.1

In reply

We were interested to read Cook-Norris and Weenig's comments on our description of 10 patients who, after allogeneic hematopoietic stem cell transplantation, developed a chronic eczema that was histopathologically characterized by features of both GVHD and dermatitis. We have described this eruption as an eczematoid form of chronic cutaneous GVHD.1 However, Cook-Norris and Weenig suggest that the clinicopathologic features point away from a chronic GVH reaction and argue that the dermatosis represents a papulosquamous variant of acute GVHD.

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