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September 15, 2008

Multiple Asymptomatic Papules on the Face—Diagnosis

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Arch Dermatol. 2008;144(9):1217-1222. doi:10.1001/archderm.144.9.1218-b

The shave biopsy specimen from 1 lesion of the nose (Figure 2 and Figure 3) showed a well-circumscribed dermal tumor characterized by a mucinous matrix with many capillaries positive for CD31 and sparse spindle- and polygonal-shaped cells, without atypical features positive for vimentin and negative for factor XIIIa. Colloidal iron staining revealed mucin deposition in the matrix of the tumor. Systemic workup included an echocardiogram, testicular ultrasonography, baseline complete blood cell count, blood chemistry profile, thyroid function studies, and measurements of growth hormone, cortisol, and free testosterone levels, all of which provided no evidence of abnormalities.

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